In addition, we do not permit the inclusion of phrases such as "data not With the submission, and you will need to provide this upon resubmission if not already Please be aware that our data availability policy requires that all numerical data underlying graphs or summary statistics are included Offers an option to publish peer-reviewed clinical study protocols.
(DOI) such that it can be cited independently in the future. Laboratory protocols in protocols.io, where a protocol can be assigned its own identifier To enhance the reproducibility of your results, we recommend that you deposit your You are ready to submit a revised version, having first consulted our Submission Checklist. You can use this link to log into the system when
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They will also be availableįor download from the link below. Notify the journal office if any appear to be missing. Resubmission date by email to present, accompanying reviewer attachments are included with this email please Please aim to resubmit within the next 60 days, unless it will take extra time toĪddress the concerns of the reviewers, in which case we would appreciate an expected If you decide to revise the manuscript for further consideration at PLOS Genetics, List of your responses to the review comments and a description of the changes you Should address the specific points made by each reviewer. Should you decide to revise the manuscript for further consideration here, your revisions We cannot, of course, promise publication at that We will not be able to accept this version of the manuscript, but we would be willing Of incomplete replication, but noted this is not essential. Reviewer 1 suggested that cytology would be a nice addition to support the conclusion The Mcm2-7 complex as well as WT, and to address a possible defect in CMG unloading. In particular, it would be important to ensure that the mcm3-2KR forms The high quality of the data presented, but raised some concerns about the current The reviewers appreciated the attention to an important problem and noted The manuscript was fully evaluated at the editorial level and by independent peer Sumoylation prevents genome rearrangements through regulated MCM loading' to PLOS
Thank you very much for submitting your Research Article entitled 'Site-specific MCM